In order to further delineate the effects of the interaction between lncRNA PAXIP1-AS1, ETS1 and KIF14 on the biological characteristics of glioma cells in vivo, oe-NC + sh-NC, oe-PAXIP1-AS1 + sh-NC, oe-NC + sh-PAXIP1-AS1, oe-PAXIP1-AS1 + sh-ETS1 and oe-PAXIP1-AS1 + sh-KIF14 were each delivered into TJ905 cells and injected into nude mice in order to examine effects on tumorigenicity. Here, PAXIP1 is linked to central nervous system cancer.