In the case of a patient suspected of having acromegaly, with poorly controlled diabetes and non-increased IGFI, there was no consensus (indeterminate) to determine GH after OGTT for diagnosis of acromegaly (S17), since the interpretation of the GH response to the OGTT when diabetes mellitus or impaired glucose tolerance is associated to suspected acromegaly may be difficult [14]; however, panelists agreed to repeat IGFI after improvement of metabolic control in this case (S18). The gene discussed is GH1; the disease is acromegaly.