However, there was a negative correlation between salivary CRP and awareness (r = − .714; p = .014) and non-judgment (r = − .720; p = .012), and a negative correlation between salivary IL-1β and satisfaction with life (r = − .874; p = .000), and a positive correlation with depression (r = .637; p = .023). Here, CRP is linked to major depressive disorder.