Low-grade inflammation was detected in H&E-stained sections in both control and Wnt1-iDTR mice following DT injection with mouse colitis histology index (MCHI) scores ranging from 1 to 6, out of a possible maximum score of 22 (3.25 ± 0.85 in controls, n = 4, vs 5.25 ± 0.48 in Wnt1-iDTR, n = 4, Fig. 7a,a’,b). Here, WNT1 is linked to colitis.