CAV1 and neoplasm: Western blot analysis showed that Sec62 expression and Sec62 targets integrin α/CAV1 expression in tumour tissues from the surgical resection in the Sec62KDgroup were much lower than that in the NC group (Fig. 4c left), while Sec62 expression and integrin α/CAV1 expression in the Sec62OE group was much higher than that in the NC group (Fig. 4c right).