In addition, arterial injury‐induced STAT3 activation is associated with suppression of LKB1 and AMPK activity in smooth muscle cells.67 It raises the possibility that lovastatin activation of LKB1‐AMPK signalling cascade not only activates p53 as shown in this study, but also inactivates STAT3 in breast cancer cells. This evidence concerns the gene STK11 and breast carcinoma.