TP53 and neoplasm: In addition, immunofluorescence analysis of mouse tumour tissues demonstrated that the number of MELK‐, Ki‐67‐ and CDK2‐positive cells was lower in the MELK inhibition group than it was in the control group, while the number of p‐ATM‐, p53‐ and p21‐positive cells was higher (Figure 5F‐K).