Experiments were performed using genome‐engineered mouse MEFs in which LRRK2 was deleted or replaced with either a kinase‐active LRRK2 harboring the most common PD‐related mutation (G2019S) or kinase‐inactive LRRK2 with the D1994A mutation (Fig EV1A). The gene discussed is LRRK2; the disease is Parkinson disease.