UGP2 and hereditary disease: UGP2 has previously been identified as a marker protein in various types of malignancies including gliomas where its upregulation is correlated with a poor disease outcome [27, 59, 61, 101, 103, 111, 112, 122], but has so far not been implicated in genetic diseases and it has been speculated that this is given its essential role in metabolism [38].