STX1B and epilepsy: An epilepsy‐related mutation in SCN8A was associated with temperature‐sensitive protein expression and function.66 Other genetic epilepsies with fever‐induced seizures include those due to certain mutations in the genes GABRG2, CHD2, STX1B: Temperature elevation can affect brain thermal regulation and epileptiform discharges and induce seizures in models carrying certain mutations in GABRG267 or STX1B. 68 Moreover, seizures in many epilepsies, of all types, are more frequent with psychological stress.