AKT1 and breast cancer: The hyperactivation of the PI3K–AKT–mTOR pathway is a marker of poor prognosis in several human cancers, such as oesophageal squamous cell carcinoma176 and breast cancer.177 Yu et al.178 recently observed that pterostilbene, an antioxidant compound primarily found in blueberries, slows down the progression of mantle cell lymphoma by targeting the PI3K–AKT–mTOR pathway.