High intracellular iron level has been verified to contribute to metastasis progression.22 EGFR also plays a role in regulating iron homoeostasis to increase iron import for cancer cell.23 The wound-healing assay and Transwell assay were performed to determine the effect of the iron supplement on the motility and invasive capacities of NPC cells. The gene discussed is EGFR; the disease is nasopharyngeal carcinoma.