VEGFA and cancer: Examples include imaging human epidermal growth factor receptor 2 (HER2) using the tracer 111In-trastuzumab, vascular endothelial growth factor A (VEGFA) using 89Zr-bevacizumab7 and oestrogen receptor expression using [18F] fluoroestradiol (18F-FES).8,9 However, functional cancer imaging has long exploited the high metabolic requirements of tumour cells for clinical purposes and hence significant opportunity exists to use these techniques to image ‘cancer metabolism’.