Glucose transporter-1 or GLUT1 is an important protein that facilitates the transport of glucose across the plasma membranes of cancer cells.21 Our results demonstrate that PKD1 overexpression in PanCa cells, HPAF-II and BxPC3, results in an upregulation of protein as well as mRNA expression of GLUT1 (Fig. 4a–d). The gene discussed is PKD1; the disease is cancer.