Similar H3K27ac profiles were observed at the same loci in multiple ADRN subtype neuroblastoma cell lines with high level of LMO1 expression but not in the MES subtype neuroblastoma cell lines with low level of LMO1 expression or in the T-ALL Jurkat cell line (Supplementary Fig. 4a). The gene discussed is LMO1; the disease is acute lymphoblastic leukemia.