MARCHF1 and urinary bladder cancer: Moreover, to verify the working axis of ciRs-6/miR-653/March1, when miR-653 was co-overexpressed with ciRs-6 in bladder cancer cells, the level of March1 was obviously decreased to a level that was similar to what was observed in wild-type cells (here, as shown in vector) (Figure 5F–5H).