Silencing March1 inhibits proliferation, migration and invasion of ovarian cancer cells by affecting the NF-κB and Wnt/β-catenin pathways [16]; Xie L et al. demonstrated that March1 promotes tumor progression of hepatocellular carcinoma via regulation of the PI3K-AKT pathway [17, 18]. Here, AKT1 is linked to hepatocellular carcinoma.