CDH1 and colorectal carcinoma: After credibility assessment and validation, we identified a total of 12 genetic loci credibly associated with CRC risk, of which 6 loci (MUTYH, SMAD7, 8q24, 8q23.3, 11q23.1, 20p12.3) were also classified as credibly associated with CRC risk in the previous field synopses and the other 6 loci (TGFB1, TERT, CDH1, RHPN2, BMP2 and 10p14) are novel findings as they have not been assessed or reported as credible risk loci in the previous field synopses.