Most frequently found, unsurprisingly, were genes associated by GWAS to diabetes or diabetes-related cardio-metabolic traits (cluster 3: MYO3B, cluster 4: DAPK1, cluster 5: LPIN2, cluster 7: SAMD4A and FHIT, cluster 8: ERG and PLCB1, cluster 12: MYT1L, cluster 15: UBE2WP1, cluster 16: ADARB2, CDKAL1, and CLIP1, cluster 17: C8orf37-AS1, cluster 21: FHOD3 and MCF2L, cluster 24: MTCL1, cluster 26: NTM, cluster 31: PCDH15, CDH4, and DCTD, cluster 31: KLF12, cluster 39: FHOD3, cluster 45: IGF1R, BCAS3, and TENM4, cluster 46: NRXN3). The gene discussed is IGF1R; the disease is diabetes mellitus.