The differentially elevated levels of AGE (Geo Mean 11.5 pg/ml in TB-DM vs 7.8 pg/ml in TB) and sRAGE (Geo Mean 614.6 pg/ml in TB-DM vs 369.6 pg/ml in TB) persisted through the completion of ATT, whereas the difference in S100A12 levels (Geo Mean 773.1 pg/ml in TB-DM vs 897.7 pg/ml in TB) was extinguished by month 6. The gene discussed is S100A12; the disease is tuberculosis.