IGFBP3 and acromegaly: A recent article from Gao et al. (2018) included 102 acromegalics and 143 control subjects to determine the effect of the rs2854744 A > C SNP at the −202 locus of insulin-like growth factor binding protein-3 (IGFBP3) and whether it constitutes a risk factor for acromegaly [55].