TNF and Sepsis: Moreover, green and black teas (70 mg/kg BW) and their related components, such as EGCG (10 mg/kg BW), theaflavins (9 mg/kg BW), and caffeine (18 mg/kg BW), effectively protected against murine sepsis, which could lie in modulating neutrophil influx and preventing neutrophil accumulation in lungs, decreasing systematic TNF-α and IL-6, suppressing tissue inducible nitric oxide synthase (iNOS) and COX-2, and increasing IL-10 [93].