CBFB and acute myeloid leukemia: RUNX1 is involved in t(8;21)(q22;q22) and t(12;21)(p13;q22) in acute myeloid and lymphocytic leukemias, and CBFB is rearranged in acute myeloid leukemias by inv(16)(p13;q22), t(16;16), and del(16)(q22).