RUNX1 and acute lymphoblastic leukemia: We next treated the three ETV6-RUNX1 cell lines with the conventional ALL chemotherapeutics dexamethasone (dex), cytarabine (AraC), vincristine (VCR), daunorubicine (dauno), and L-asparaginase (L-Asp) (Sigma-Aldrich) for 48 h.