Our group has shown that nerve growth factor (NGF) and its high affinity receptor tropomyosin receptor kinase A (TRKA) increase during EOC progression [9], activating phosphoinositide 3-kinase/ protein kinase B (PI3K/AKT) and mitogen-activated protein kinase /extracellular signal-regulated kinase (MAPK/ERK) signaling pathways, resulting in enhanced tumor growth [10]. Here, NGF is linked to neoplasm.