FLT3 is widely expressed on leukemic cells in AML, and at present a clinical study is conducted in which we evaluate the Fc-optimized FLT3 mAb 4G8-SDIEM (FLYSYN) to induce NK cell reactivity in AML patients with minimal residual disease (NCT02789254). This evidence concerns the gene FLT3 and acute myeloid leukemia.