TNFSF10 and cancer: BITC has been reported to exert chemopreventive effects in several cancer cells by inducing anti-angiogenesis, apoptosis, cell-cycle arrest, anti-metastasis, and anti-tumorigenesis effects, and has been described to have synergistic effects with TRAIL, cisplatin, sulforaphane, phenethyl isothiocyanate, and radiation treatments [38].