Tindall et al., 2019 [9] observed significant reductions in homeostasis model assessment of insulin resistance (HOMA-IR) (WMD −0.23; 95% CI −0.40, −0.06; I2 = 51.7%) and fasting insulin (WMD −0.40 μIU/mL; 95% CI −0.73, −0.07 μIU/mL; I2 = 49.4%) after nut consumption from meta-analyses of 19 RCTs [61,66,68,74,86,91,92,96,97,99,100,103,104,105,107,109,110,114,117] and 28 RCTs [58,61,63,66,67,68,74,86,91,92,93,95,96,97,99,100,101,102,103,104,105,107,110,112,113,114,116,117], respectively. This evidence concerns the gene INS and Insulin resistance.