ITIH4 and AIDS: The temporal expression of HIV-1 gp120 under the control of the LEO160 promoter was studied and the results showed that the mRNA transcription levels of HIV-1 gp120 and the total HIV-1 gp120 protein production in cells infected with MVA-LEO160-gp120 was significantly upregulated during most of the times studied, compared with cells infected with the HIV/AIDS vaccine candidate MVA-B, expressing the HIV-1BX08 gp120 under the control of the widely used sE/L promoter [62].