Thus, the MVA-LEO160-gp120 vector enhanced the levels of intracellular and extracellular production of gp120 during infection, although there was no apparent difference between the vectors in the gp120 secreted levels at 6 and 24 h, probably due to the extensive cytopathic effect and induction of apoptosis triggered by the MVA vector. This evidence concerns the gene ITIH4 and infection.