TNF and lymphangioma: Many cytokines, including tumor necrosis factor (TNF-α), interleukins (IL-1 and IL-6), as well as chemokines and their receptors (MIP-1 α, MIP-1β, RANTES, eotaxin, eotaxin-2, IL-8, CCR1, CCR3, CCR5, CXCR1, and CXCR2) are involved in the development of LM [11].