IL7R and immune system disorder: In addition to SCID and MS, polymorphisms in the IL7RA gene are also shown in association with other immune diseases, such as the involvement of rs6897932 in type 1 diabetes (T1D) [51] and rheumatoid arthritis (RA) [52], rs193922641 (p.C118Y) in Omenn syndrome (OS) [39], rs3194051 (p.I356V) in T1D [51], rs1494555 (p.V138I) in graft versus host disease (GvHD) [47], rs10213865 (intronic) in sarcoidosis [54], rs11567764 (p.K187=) in tuberculosis [43], and rs1494558 (p.I66T) in IgA nephropathy (IgAN) [44] (Table 1).