BCL11B and acute lymphoblastic leukemia: Moreover, while the 14q32 region and BCL11B are known to be frequently altered in hematological malignancies [34], we found only three additional cases of lymphoid malignancies carrying the t(2;14)(q21;q32) translocation, including biphenotypic leukemia [35] and acute lymphoblastic leukemia [36,37,38].