Interestingly, it has been reported that statins are pleiotropic drugs, and, in addition to their effect on lowering cholesterol, they are involved in the regulation of processes implicated in DMD progression, such as autophagy and NADPH oxidase 2-mediated oxidative stress (see also Section 3.3Reactive Oxygen/Nitrogen Species (ROS/RNS)) [22], and angiogenesis [23]. Here, CYBB is linked to Duchenne muscular dystrophy.