SOD1 and amyotrophic lateral sclerosis: A genetic analysis of these familial ALS (fALS) cases showed that mutations in superoxide dismutase 1 (SOD1), in TAR DNA binding protein (TARDBP) encoding TDP-43, and in fused in sarcoma (FUS), as well as hexanucletoide repeat expansions in chromosome 9 open reading frame 72 (C9ORF72) are the most common genetic causes of ALS [2].