Currently, to investigate the role of this drug on renal cell cancer, an early phase I trial (SPARC-1, NCT04028245) is enrolling patients to be treated with the association of canakinumab and spartalizumab (an anti-PD1 monoclonal antibody) as neoadjuvant treatment before radical nephrectomy. Here, RPL17 is linked to renal cell adenocarcinoma.