When considering the PD1 axis as prognostic factor, a study by Abbas et al. on patients undergoing radical renal tumor surgery reported that neither PD-1 positive tumor-infiltrating mononuclear cells or intratumoral PD-L1 expression seemed to significantly impact tumor aggressiveness or clinical outcome in ncc-RCC specimens [166]. The gene discussed is RPL17; the disease is renal cell adenocarcinoma.