We observed an increase in JAK2 phosphorylation in lysates from both HPV16 positive (HPV16+; SiHa and CaSKi) and HPV18 positive (HPV18+; SW756 and HeLa) cervical cancer cell lines when compared to HPV negative (HPV−; C33A and DoTc2) cervical cancer cells. The gene discussed is JAK2; the disease is cervical cancer.