MSCs are also able to sustain viability and migration of multiple myeloma (MM) cells: MM cells transfer miR146a-containing EVs into MSCs, leading to enhanced cytokine and chemokine release, including C-X-C Motif Chemokine Ligand 1 (CXCL1), interleukin 6 (IL-6), and Monocyte Chemoattractant Protein-1 (MCP-1) [118]. Here, CXCL1 is linked to plasma cell myeloma.