Quantitative RT-PCR Taqman analysis (RT-qPCR) revealed a drastically reduced expression of three genes specifically expressed by mature adipocytes, namely Adiponectin (AdipoQ), Fatty Acid Binding Protein 4 (FABP4) and Hormone Sensitive Lipase (HSL), in adipose cells induced to differentiate during co-culture with the tumor cells (Figure 4A). The gene discussed is LIPE; the disease is neoplasm.