Inverse correlation between TMPRSS4 methylation and SHOX2 methylation status was also found for plasma samples in early NSCLC (r = −0.56; p = 0.007) but not for late NSCLC samples (r = 0.01; p = 0.9) (Figure S3, Supplementary Materials). This evidence concerns the gene SHOX2 and non-small cell lung carcinoma.