Interestingly, the analysis of distribution of the genotypes and alleles of the c.-844G > T – TPH2 (rs4570625) polymorphism showed that the G/G homozygote and the G allele increased the risk of stroke by more than 30 times (p < 0.001), while the G/T genotype of the same SNP decreased the risk by nearly 27 times (p < 0.001). The gene discussed is TPH2; the disease is Stroke.