YAP activity in cancer cells induces the expression of cytokines such as IL-6 (interleukin 6), CXCL5 (C-X-C motif chemokine 5), and granulocyte-macrophage colony stimulating factors that stimulate the recruitment of myeloid-derived suppressor cells (MDSCs) [103,104]. The gene discussed is YAP1; the disease is cancer.