CXCR4 and posterior cortical atrophy: A vital mechanism by which PCa cells home to the bone is mediated by Chemokine (C-X-C motif) Receptor type 4 (CXCR4)/Chemokine (C-X-C motif) Ligand 12 (CXCL12) signaling, and multiple investigations have documented the seminal role of CXCR4/CXCL12 chemokine axis in PCa homing to the bone [7,8,9,10].