Assessment of sensitivity and specificity of the binding of nanoconjugates UCNP@SiO2-LPG-MIL-38, was performed by incubation with urothelial carcinoma cells with high expression of Glypican-1 (T24) and urothelial carcinoma cells with low expression of Glypican-1 (C3). The gene discussed is GPC1; the disease is urothelial carcinoma.