STAT3 and neoplasm: In addition, consistent with the in vitro results for HeLa and CaSki cervical cancer cells, Western blot analysis indicated that treatment with TMS-TMF-4f inhibited the phosphorylation of STAT3 and its associated proteins, Mcl-1, cyclin D1, survivin, and c-Myc, in the tumor tissues of the xenograft mice (Figure 7c).