In murine 4T1 and LLC cells (breast and lung tumor, respectively), as well as in human CAPAN-1 pancreatic adenocarcinoma, the VEGFA and VEGFC IRESs are activated after 24 hr of hypoxia whereas the EMCV IRES is not activated (Morfoisse et al., 2014). This evidence concerns the gene VEGFC and pancreatic adenocarcinoma.