Intriguingly, the autophagy inhibitor 3-MA and lysosome inhibitor CQ failed to alter the protein level of OX-42 (Fig. 6e), while the microglial activation inhibitor minocycline succeeded in reversing the increases in protein levels of LC3, p62 and LAMP1 induced by CCH (Fig. 6b–d). Here, LAMP1 is linked to columnar cell hyperplasia of the breast.