IL6 and neoplasm: Regarding relationship between FOXP3 and STAT3, Hossain et al. revealed that FOXP3 silencing decreased the expression of STAT3-related genes such as IL-6, VEGFA, C-Myc, BCL2L1, and CCND1, but not TGF-β1 in tumor induced regulatory T cells by qRT-PCR analysis [22].