CD34 and acute megakaryoblastic leukemia: These could be CD34− blast cells or leukemia stem cells, which were associated with worsened prognosis and sensitivity to therapy.24 Other megakaryocyte-like large cells were also captured (Supplementary Fig 6b), and their presence was associated with acute megakaryoblastic leukemia.25 The enrichment of CD34− blast cells and megakaryocyte-like cells using the BCB highlight the capability of this technique to identify other leukemia subtypes potentially, and can be subsequently utilized for correlation to patient overall survival.