In our search for regulators of FOXM1 activity, we assayed various members of a local chemical library for their inhibition of breast cancer cell proliferation and expression of FOXM1-signature genes, and we obtained a number of initial hits that were then expanded to a family of 1,1-diarylethylene mono and diamines, and their corresponding methiodide salts. This evidence concerns the gene FOXM1 and breast carcinoma.