In autoimmune diseases of multiple sclerosis (MS), there were no significant allelic associations of SNPs rs4753426 and rs10830963 in MTNR1b gene with susceptibility to MS, but the rs10830963-rs4753426 G-T haplotype associated with the risk of MS in the progressive MS group [23]. The gene discussed is MTNR1B; the disease is multiple sclerosis.