Lower IL-10 production was observed in T2D only after Pam3Cys stimulation (median (pg/ml), 0.0 (0-25.3) in T2D and 6.5 (0-139.5) in healthy subjects) and after M. tuberculosis infection (median (pg/ml), 0.0 (0-6.1) in T2D and 0 (0-270) in healthy subjects) (P < 0.05, Figures 2(a)–2(c)). The gene discussed is IL10; the disease is type 2 diabetes mellitus.