TLR4 and type 2 diabetes mellitus: In concordance with Khondkaryan et al., we observed that T2D patients express TLR-2 and TLR-4 in monocytes at the same level as healthy subjects; although the healthy population was overweight, a previous report demonstrated that subjects with T2D had significantly elevated mRNA levels of TLR-2 and TLR-4 compared with nondiabetic obese subjects [18].